Avoid culture failure with a Brewer’s B27-based supplement that provides a consistent neuronal culture experience for CNS-derived or human pluripotent stem cell (hPSC)-derived cells.
NeuroCult™ SM1 (STEMCELL Modified-1) Neuronal Supplement is based on the published formulation (Brewer et al. Brain Res, 1989) and standardized to more reproducibly support survival and maturation of functional neurons. Cultures with this serum-free supplement feature increased neurite outgrowth and branching in short- and long-term cultures. NeuroCult™ SM1 may also be used as a serum-replacement supplement for various customizable applications, such as neurotoxicity assays and calcium imaging.
For your convenience, NeuroCult™ SM1 is included as a component of multiple BrainPhys™ Neuronal Medium culture kits for primary and hPSC-derived neurons (Catalog #05792, 05793, 05794, and 05795). For further details, see the performance data with BrainPhys™ below .